Современные перспективы мультиомных исследований бактерий из группы Bacteroides
Основное содержимое статьи
Аннотация
В этом обзоре рассматриваются мультиомные (геномные, транскриптомные и протеомные) подходы к изучению бактерий группы Bacteroides spp., которые являются наиболее распространенными анаэробами в толстой кишке человека и ответственны за более чем половину всех внутрибрюшных анаэробных инфекций. Эти многомерные подходы позволили идентифицировать факторы вирулентности, гены устойчивости к противомикробным препаратам и другие функциональные элементы генома Bacteroides. Эта информация имеет решающее значение для понимания патогенного потенциала этих бактерий и их роли в развитии анаэробных инфекций. В этом обзоре рассматривается транскрипционный ответ Bacteroides после воздействия субингибирующих концентраций антимикробных препаратов, а также основные методы протеомного анализа и достижения в изучении протеома Bacteroides. В целом, современные перспективы мультиомических исследований Bacteroides подчеркивают возможность интеграции различных омических подходов для более полного понимания их биологии, функциональных характеристик и экологической роли в экосистеме кишечника.
Информация о статье
##plugins.generic.dates.accepted## 2025-09-20
##plugins.generic.dates.published## 2025-09-22
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