Clinical and Functional Characteristics of Atrial Fibrillation in Patients With and Without Ischemic Heart Disease

Abstract

This article examines atrial fibrillation (AF) in patients with and without ischemic heart disease (IHD), focusing on their clinical and laboratory-instrumental characteristics. The study assessed anthropometric parameters (sex, age, weight, height, body mass index), AF types, primary and comorbid diagnoses, echocardiographic data (ejection fraction), lipid profile and biochemical markers (ALT, AST, total cholesterol, LDL), scores on the CHA₂DS₂-VASc and HAS-BLED scales, as well as data on surgeries and prescribed pharmacotherapy. The results indicate that patients with IHD more frequently present with persistent forms of AF, endomorphic body type, signs of endogenous obesity, consistently accompanying arterial hypertension, elevated CHA₂DS₂-VASc and HAS-BLED risk scores, and are prescribed a higher average number of medications, reflecting a more complex overall clinical status and requiring more meticulous long-term clinical supervision and careful adjustment of therapy according to dynamic patientrisk profiles.
The identified differences between groups highlight the necessity of a comprehensive and individualized approach to the diagnosis and treatment of atrial fibrillation, particularly in patients with ischemic heart disease.